Interaction study of moxifloxacin with Cu(II) ion using square-wave voltammetry and its application in the determination in tablets
Main Article Content
Abstract
(MOXI) in tablets by its interaction with Cu(II) ion and subsequent electrochemical reduction at hang-
ing mercury drop electrode (HMDE). A well-defined reduction peak at -0.21 V vs. Ag/AgCl in
Phosphate buffer 0.04 mol L -1 pH 8.0 was observed for the complex reduction MOXI-Cu(II), using
square-wave voltammetry (SWV). Using a 10 s of accumulation time at -0.40 V was found a limit
detection of 3.60x10 -8 mol l -1 . The obtained results have shown good agreement with those obtained by
spectrophotometric method.
Metrics
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
The corresponding author transfers the copyright of the submitted manuscript and all its versions to Eclet. Quim., after having the consent of all authors, which ceases if the manuscript is rejected or withdrawn during the review process.
When a published manuscript in EQJ is also published in other journal, it will be immediately withdrawn from EQ and the authors informed of the Editor decision.
Self-archive to institutional, thematic repositories or personal webpage is permitted just after publication. The articles published by Eclet. Quim. are licensed under the Creative Commons Attribution 4.0 International License.
References
C. Ostergaard, T.K. Sorensen, J.D. Knudsen, N.F. Moller,
Antimicrob. Agents Chemother. 42 (1998) 1706.
K. Vishwanathan, M.G. Bartlett, J.S. Stewart, J. Pharm.
Biomed. Anal. 30 (2002) 961.
D.J. Biedenbach, M.S. Barrett, M.A.T. Croco, R.N. Jones,
Diagn. Microbiol. Infect. Dis. 32 (1998) 45.
R. Wise, J.M. Andrews, G. Marshall, G. Hartman,
Antimicrob. Agents Chemother. 43 (1999) 1508.
T.E. Spratt, S.S. Schultz, D.E. Levy, D. Chen, G. Schluter,
G.M. Williams, Chem. Res. Toxicol. 12 (1999) 809.
H. Stass, D. Kubitza, Clin. Pharmacokin. 40 (2001) 57.
M. Córdoba-Díaz, M. Córdoba-Borrego, D. Córdoba-
Díaz, J. Pharm. Biomed. Anal. 18 (1998) 565.
I. Turel, Coord. Chem. Rev. 32 (2002) 27.
F. Belal, A.A. Al-Majed, A.M. Al-Obaid, Talanta 50
(1999) 765.
V. Kapetanovi, Lj. Milovanovi, M. Erceg, Talanta 43
(1996) 2123.
M.S. Rizk, F. Belal, F.A. Ibrahim, S.M. Ahmed, Z.A.
Sheribah, Electroanalalysis 12 (2000) 531.
N. Zhang, X. Zhang, Y. Zhao, Talanta 62 (2004) 1041.
N. Zhang, X. Zhang, Y. Zhao, Microchem. J. 75 (2003)
I. Turel, N. Bukovec, E. Farkas, Polyhedron 15 (1996) 269.
I. Turel, A. Golobi?, A. Klav?ar, B. Pihlar, P. Buglyó, E.
Tolis, D. Rehder, K. Sep?i?, J. Inorg. Biochem. 95 (2003) 199.
N. Erk, Anal. Bioanal. Chem. 378 (2004) 1351.
J.A. Ocana, F.J. Barragan, M. Callejón, Analyst 125
(2000) 2322.
V.S. Ferreira, C.B. Melios, M.V.B. Zanoni, N.R.
Stradiotto, Analyst 121 (1996) 263.
G. Popovi?, Lj. Milovanovi?, V. Kapetanovi?, J. Pharm.
Biomed. Anal. 18 (1998) 859.
E. Jiménez-Lozano, I. Marqués, D. Barrón, J.L. Beltrán,
J. Barbosa, Anal. Chim. Acta 464 (2002) 37.
V.S. Ferreira, M.V.B. Z.anoni, M. Furlan, A.G. Fogg,
Anal. Chim. Acta 351 (1997) 105.
V.S. Ferreira, M.V.B. Zanoni, A.G. Fogg, Anal. Chim.
Acta 367 (1998) 255.
V.S. Ferreira, M.V.B. Zanoni, A.G. Fogg, Anal. Chim.
Acta 384 (1999) 159.
The United States Pharmacopoeia, The National
Formulary, USP 24, NF 19, USP Convention Inc., 12601, MD
, p.2151.