Interaction study of moxifloxacin with Cu(II) ion using square-wave voltammetry and its application in the determination in tablets

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Magno Aparecido Gonçalves Trindade
Patrícia Alessandra da Cruz Cunha
Tatiane Alfonso de Araujo
Glaucia Maria da Silva
Valdir Souza Ferreira

Abstract

This work presents an electroanalytical method for the determination of moxifloxacin
(MOXI) in tablets by its interaction with Cu(II) ion and subsequent electrochemical reduction at hang-
ing mercury drop electrode (HMDE). A well-defined reduction peak at -0.21 V vs. Ag/AgCl in
Phosphate buffer 0.04 mol L -1 pH 8.0 was observed for the complex reduction MOXI-Cu(II), using
square-wave voltammetry (SWV). Using a 10 s of accumulation time at -0.40 V was found a limit
detection of 3.60x10 -8 mol l -1 . The obtained results have shown good agreement with those obtained by
spectrophotometric method.

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How to Cite
Trindade, M. A. G., Cunha, P. A. da C., de Araujo, T. A., da Silva, G. M., & Ferreira, V. S. (2006). Interaction study of moxifloxacin with Cu(II) ion using square-wave voltammetry and its application in the determination in tablets. Eclética Química, 31(1), 31–38. https://doi.org/10.26850/1678-4618eqj.v31.1.2006.p31-38
Section
Original articles

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