Interaction study of moxifloxacin with Cu(II) ion using square-wave voltammetry and its application in the determination in tablets
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Keywords

moxifloxacin
electroanalysis
complexation of moxifloxacin

How to Cite

Trindade, M. A. G., Cunha, P. A. da C., de Araujo, T. A., da Silva, G. M., & Ferreira, V. S. (2006). Interaction study of moxifloxacin with Cu(II) ion using square-wave voltammetry and its application in the determination in tablets. Eclética Química, 31(1), 31–38. https://doi.org/10.26850/1678-4618eqj.v31.1.2006.p31-38

Abstract

This work presents an electroanalytical method for the determination of moxifloxacin
(MOXI) in tablets by its interaction with Cu(II) ion and subsequent electrochemical reduction at hang-
ing mercury drop electrode (HMDE). A well-defined reduction peak at -0.21 V vs. Ag/AgCl in
Phosphate buffer 0.04 mol L -1 pH 8.0 was observed for the complex reduction MOXI-Cu(II), using
square-wave voltammetry (SWV). Using a 10 s of accumulation time at -0.40 V was found a limit
detection of 3.60x10 -8 mol l -1 . The obtained results have shown good agreement with those obtained by
spectrophotometric method.
https://doi.org/10.26850/1678-4618eqj.v31.1.2006.p31-38
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