Keywords
Cephalosporium aphidicola
ent-kaur-16-en-19-ol
ent-kauran-16β
19-diol
ent-kauran-16β,17
19-triol
How to Cite
Abstract
The use of microorganisms to induce chemical modifications in organic molecules is a very useful tool in organic synthesis, to obtain biologically active substances. The fungus Cephalosporium aphidicola is known by its ability to hydroxylate several skeleton positions of many classes of organic compounds. In this work, the microbial transformation of ent-kaur-16-en-19-ol (1) by C. aphidicola, afforded two hydroxylated compounds, ent-kauran-16b,19-diol (2) and ent-kauran-16b,17,19-triol (3). Their structures were established by 1D and 2D-NMR studies. Both compounds were tested for their action on the growth of radical and shoot of Lactuca sativa.References
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