Keywords
dermal applications
biodegradable polymers
thermal processing
wound healing
How to Cite
Abstract
This study focused on developing films from physically cross-linked starch hydrogel with glycerol, utilizing short cooling and heating cycles to enhance cross-linking via the freeze-thaw process. Characterization revealed that 30% glycerol promoted physical cross-linking, further intensified by the thermal cycles, leading to increased film density (AG-R1, AG-R2, and AG-R4). The films demonstrated favorable physicochemical properties for reparative dressings, including easy handling, flexibility, high swelling capacity, water vapor permeability, and low solubility. Notably, the AG-R2 film exhibited the most significant changes, showing increased density and reduced thickness. This indicates a distinct morphology compared to the other films, suggesting an entanglement that restricts solvent molecules (water) incorporation during testing.
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