Biheterocyclic ligands: synthesis, characterization and coordinating properties of bis(4-amino-5-mercapto-1,2,4-triazol-3-yl) alkanes with transition metal ions and their thermokinetic and biological studies

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Published: Sep 29, 2008
DOI: https://doi.org/10.26850/1678-4618eqj.v33.3.2008.p29-42
Keywords:
biheterocyclic ligands, Co(II), Ni(II) and Cu(II) complexes, synthesis, characterization, thermal degradation, kinetic parameters, biological activities

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Hussein Al-Maydama
Sana’a University, Faculty of Science, Sana’a, Yemen.
https://orcid.org/0000-0002-0455-8074
Tajedin Yahya Al-Ansi
Sana’a University, Faculty of Science, Sana’a, Yemen.
Yasmin M. S. Jamil
Sana’a University, Faculty of Science, Sana’a, Yemen.
A. H. Ali
Sana’a University, Faculty of Science, Sana’a, Yemen.

Abstract

The Co(II), Ni(II) and Cu(II) metal ions complexes of Bis(4-amino-5-mercapto-1,2,4-triazol-3-yl) alkanes (BATs) have been prepared and characterized by elemental analysis, conductivity measurements infrared, magnetic susceptibility, the electronic spectral data and thermal studies. Based on spectral and magnetic results, the ligands are tetradentate coordinating through the N and S-atoms of BATs; six-coordinated octahedral or distorted octahedral and some times four-coordinated square planar were proposed for these complexes. Activation energies computed for the thermal decomposition steps were compared. The ligands and their metal complexes were tested in vitro for their biological effects. Their activities against two gram-positive, two gram-negative bacteria and two fungal species were found to vary from moderate to very strong.

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How to Cite
Al-Maydama, H., Al-Ansi, T. Y., Jamil, Y. M. S., & Ali, A. H. (2008). Biheterocyclic ligands: synthesis, characterization and coordinating properties of bis(4-amino-5-mercapto-1,2,4-triazol-3-yl) alkanes with transition metal ions and their thermokinetic and biological studies. Eclética Química, 33(3), 29–42. https://doi.org/10.26850/1678-4618eqj.v33.3.2008.p29-42
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Vol. 33 No. 3 (2008): Eclética Química
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Original articles
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References

D.-K. Kim, J. Kim, and H.-J. Park, Bioorganic & Medicinal Chemistry Letters. 14(10) (2004) 2401.

B. Modzelewska-Banachiewicz, J. Banachiewicz, A. Chodkowska, E. Jagiello-Wojtowicz, and L. Mazur, European

Journal of Medicinal Chemistry. 39(10) (2004) 873.

L. Tian, Y. Sun, H. Li, et al, Journal of Inorganic Biochemistry. 99(8) (2005) 1646.

J. Liu, L. Li, H. Dai, Z. Liu, and J. Fang, Journal of Organometallic Chemistry. 691(12) (2006) 2686.

M. Serdar, N. Gumrukcuoglu, S. Alpay Karaoglu and N.

Demirbas, Turk J Chem. 31 (2007) 315.

N. Demirbas, A. Demirbas, S. A. Karaoglu and E. Celik,

ARKIVOC. I (2005) 75.

P. F. Xu, X. W. Sun, L. M. .Zhang and Z. Y. Zhang, J. Chem. Research (S). (1999) 170.

Z. Y. Zhang, X. Chen, L. L. Wei and Z. L. Ma, Chemical

Research in Chinese Universities. 2 (1991) 129.

X. Zhu, Y. M. Zhang, B. L. Li and Y. Zhang, Journal of

Coordination Chemistry. 59(5) (2006) 513.

P. Thakur, V. Chakravortty and K. C. Dash , Polyhedron.

(9) (1997) 1417.

K. C. Rout, R. R. Mohanty, S. Jena and K. C. Dash,

Polyhedron. 15(56) (1996) 1023.

J. A. Joule, K. Nills, G. F. Smith, Heterocyclic Chemistry,

Chapman and Hall, London, 3rd edn., 1995.

K.B. Gudasi, P. B. Maravalli and T. R. Goudar, J. Serb.

Chem. Soc. 70(4) (2005) 643.

T. A. Khan and Shahjahan, Synthesis and Reactivity in

Inorganic, Metal-Organic, and Nano-Metal Chemistry. 31(6)

(2001) 1023.

A. W. Coats and J. P. Redfern, “Kinetic parameters from

thermogravimetric” Nature. 201 (1964) 68.

A. E. Liberta and D. X. West, BioMetal, 5(2) (1992) 121.

E. Rodriguez-Fernandez, J. L. Manzano, J. J. Benito, R.

Hermosa, E. .Monte, J..J. Criado, Journal of Inorganic Biochemistry, 99(8) (2005) 1558.

G. K. Zahariou, E. Gavrielatos, I. M. Kalogeras, G.

Athanasellis, A. Vassilikou-Dova, O. Igglessi-Markopoulou,

J. Markopoulos, Radiation Effects and Defects in Solids. 157(6-12) (2002) 1057.

K. Zamani, K. Faghihi, M.S, Mehranjani, Pol. J. Pharmacol. 55 (2003) 1111.

A.I. Vogel “A Text Book of Quantitative Inorganic Analysis” Longmans, London ,1961.

A. M. Sh El-Sharief, Y. A. Ammar, M. A. Zahran, A. H.

Ali and M. S. A. El-Gaby, Afindad. 60(503) (2003) 32.

Z. Szafran, R. M. Pike and M. M. Singh, “Microscale

Inorganic Chemistry” John Wiley,lNC, New York , 1991.

R. R. Amin, A. T. Al-Subaie, B. A. El-Gamal, A.M.

Mahasneh and I.S. Al-Naimi, Journal of the Medica Research

Institute. 22(1) (2001) 1.

A. A. El-Asmy, M. E. Khalifa, and M. M. Hassanian,

Synth. React. Inorg. Met.-Org. Chem., 31(10) (2001) 1787.

M. Arshad, Saeed-ur-Rehman, S. A. Khan, K. Masud, N.

Arshad and Abdul Ghni, Thermochimica Acta. 364 (2000) 143.

K. S. Siddiqi, R. I. Kureshy, N. H. Hkan, S. Tabassum

And S. A. A. Zaidi, Inorganic Chimica Acta. 151(2) (1988) 95.

N. M. El-Metwally, I. M. Gabr, A. A. El-Asmy, A.A.

Abou-Hussen, Transition Metal Chemistry. 31 (2006) 71.

A. A. El-Asmy, M. A. Morsi and A. A. El-Shafei, Transition Met. Chem. 11 (1986) 494.

Y. Zhang, W. Ruan, X. Zhao, H. Wang and Z. Zhu,

Polyhedron. 22(12) (2003) 1535.

N. M. El-Metwally, A. A. El-Asmy, A.A. Abou-Hussen,

International Journal of Pure & Applied Chemistry. 1(1)

(2006) 75.

A. A. El-Asmy, M. E Khalifa, T. H. Rakha, M. M. Hassanian, A. M. Abdallah, Chem. Pharm. Bull.,48 (2000) 41.

A. B. P. Lever, “Inorganic Electronic Spectroscopyî,

Elsevier, Amsterdam, 1968.

A. A. El-Asmy , Synth. react. Inorg. Met.-Org. Chem.. 17

(1987) 399.

N. C. Saha, R. J. Butcher, S. Chaudhuri and N. Saha,

Polyhedron. 22(3) (2003) 383.

A. A. El-Asmy, T.Y. Al-Ansi, M..Mounir and S. A.

Ashour, Synth. React. Inorg. Met.-Org. Chem. 19(4) (1989)

G. G. Mohamed, M. .M. Omar, A. M. M. Hindy, Spectrochimica Acta. (A 62) (2005) 1140.

A. A. El-Asmy, Ph D thesis. Faculty of Science, Mansoura University, Egypt, 1981.

N. M. El-Metwally, I. M. Gabr, A. M. Shallaby And A.

A. El-Asmy, Journal of Coordination Chemistry. 58(13) (2005) 1145.

G. A. A. Al-Hazmi, M. S. El-Shahawi, I. M. Gabr And A.

A. El-Asmy, Journal of Coordination Chemistry. 58(8) (2005)

F.A. El-Saied, M.I. Ayad, R.M. Issa and S.A. Aly, , Polish

J. Chem., Inorganic Chemistry. 75 (2001) 773.

A. A. El-Asmy, T. Y. Al-Ansi, R. R. Amin, M. F. El Shahat, Trans. Metal Chem. 15 (1990) 12.

H. Al-Maydama, A. El-shekeil M. A. Khalid and A. Al-

Karbouly, Ecl. Quim., Sao Paulo. 31(1) (2006) 45.

P. B. Maravalli and T. R Goudar, Thermochimica Acta.

(1999) 35.