Spot-test identification and rapid quantitative sequential analysis of dipyrone
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Keywords

dipyrone
spot-test
analysis
qualitative
quantitative

How to Cite

Tubino, M., Biondo, A. C., Vila, M. M. D. C., Pezza, L., & Pezza, H. R. (2010). Spot-test identification and rapid quantitative sequential analysis of dipyrone. Eclética Química, 35(1), 41–46. https://doi.org/10.26850/1678-4618eqj.v35.1.2010.p41-46

Abstract

A qualitative spot-test and tandem quantitative analysis of dipyrone in the bulk drug
and in pharmaceutical preparations is proposed. The formation of a reddish-violet  color indicates a positive result. In sequence a quantitative procedure can be performed in the same flask. The quantitative results obtained were statistically compared with those obtained with the method indicated by the Brazilian  Pharmacopoeia, using the Student’s t and the F tests. Considering the concentration in a 100 μL aliquot, the qualitative visual limit of detection is about 5×10-6 g; instrumental LOD ≅ 1.4×10-4 mol L-1 ; LOQ ≅ 4.5×10-4 mol L-1.
https://doi.org/10.26850/1678-4618eqj.v35.1.2010.p41-46
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