Validation of analytical methodology for determination of Personal Care Products in environmental matrix by GC-MSMS
PDF
EPUB

How to Cite

Filippe, T. C., de Almeida Brehm Goulart, F., Mizukawa, A., & Rodrigues de Azevedo, J. C. (2018). Validation of analytical methodology for determination of Personal Care Products in environmental matrix by GC-MSMS. Eclética Química, 43(3), 30–36. https://doi.org/10.26850/1678-4618eqj.v43.3.2018.p30-36

Abstract

The presence of personal care products in the environment is recent and relatively few researches work with the quantification of this class of emerging contaminants in Brazil. However, a wide variety of these products is continuously released into the aquatic environment. The growing interest in these substances occurs mainly because they exhibit biological activity in very low concentrations, which gives great environmental relevance. The difficulty of detecting and quantifying such contaminants in the environment encourages the development and validation of appropriate analytical methods for this purpose. Therefore, the present study aims to validate a methodology and verify its efficiency in the determination of six personal care products, among them parabens and triclosan. The samples were submitted to the solid phase extraction process and were later analyzed by gas chromatography coupled with mass spectrometry for the determination of personal care products. The validation of the methodology used was based on the standards established by the National Health Surveillance Agency. The extraction and quantification method were efficient for the determination of these analytes in water samples.

https://doi.org/10.26850/1678-4618eqj.v43.3.2018.p30-36
PDF
EPUB

References

Brausch, J. M., Rand, G. M. A review of personal care products in the aquatic environment: environmental concentrations and toxicity, Chemosphere. 82 (11) (2011) 1518-1532.

Gottschall, N., Topp, E., Metcalfe, C., edwards, M., Payne, M., Kleywegt, S., Lapen, D. R. Pharmaceutical and personal care products in groundwater, subsurface drainage, soil, and wheat grain, following a high single application of municipal biosolids to a field, Chemosphere. 87 (2) (2012) 194-203.

De García, S. O., García-Encina, P. A., Irusta-Mata, R. The potential ecotoxicological impact of pharmaceutical and personal care products on humans and freshwater, based on USEtox™ characterization factors. A Spanish case study of toxicity impact scores, Sci. Total Environ. 609 (2017) 429-445.

Kolpin, D. W., Furlong, E. T., Meyer, M. T., Thurman, E. M., Zaugg, S. D., Barber, L. B., Buxton, H. T. Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance, Environ. Sci. Technol. 36 (6) (2002) 1202-11.

Halden, R. U., Paull, D. H. Co-occurrence of triclocarban and triclosan in U.S. water resources, Environ. Sci. Technol. 39 (6) (2005) 1420-1426.

Mcavoy, D. C., Schatowitz, B., Jacob, M., Hauk, A., Eckhoff, W. S. Environmental Chemistry Measurement of Triclosan In Wastewater Treatment Systems, Environ. Toxicol. Chem. 21 (7) (2002) 1323-1329.

Boberg, J., Taxvig, C., Christiansen, S., Hass, U. Possible endocrine disrupting effects of parabens and their metabolites, Reprod. Toxicol. 30 (2) (2010) 301-312.

Perez. S., Barcelo. D. Application of advanced MS techniques to analysis and identification of human and microbial metabolites of pharmaceuticals in the aquatic environment, TrAC. 26 (6) (2007) 494-514.

Sui, Q., Huang, J., Deng, S., Yu, G., Fan, Q. Occurrence and removal of pharmaceuticals, caffeine and DEET in wastewater treatment plants of Beijing, China, Water Res. 44 (2010) 417-426.

Scognamiglio, V., Antonacci, A., Patrolecco, L., Lambreva, M. D., Litescu, S. C., Ghuge, S. A., Rea, G. Analytical tools monitoring endocrine disrupting chemicals, TrAC. 80 (2016) 555-567.

Toxnet, toxnet.nlm.nih.gov. Acesso em julho de 2017.

Ide, A. H., Cardoso, F. D., Marques, M. DOS S. Utilização da Cafeína como Indicador de Contaminação por Esgotos Domésticos na Bacia do Alto Iguaçu, Rev. Bra. Recur. Hídricos. 18 (2) (2013) 201–211.

ANVISA; Agência Nacional de Vigilância Sanitária; Resolução - RE nº 475, de 19 de março de 2002.

ANVISA; Agência Nacional de Vigilância Sanitária; Resolução - RE nº 899, de 29 de maio de 2003.

INMETRO; Instituto Nacional de Metrologia, Normalização e Qualidade Industrial; Orientações sobre validação de métodos de ensaios químicos; DOQ-CGCRE-008, março de 2003.

Kramer, R. D., Mizukawa, A., Ide, A. H., Marcante, L. O. Determinação de anti-inflamatórios na água e sedimento e suas relações com a qualidade da água na bacia do Alto Iguaçu, Curitiba-PR, Rev. Bra. Recur. Hídricos. 20 (2015) 657–667.

Regueiro, J., Becerril, E., Garcia-jares, C., Llompart, M. Trace analysis of parabens, triclosan and related chlorophenols in water by headspace solid-phase microextraction with in situ derivatization and gas chromatography-tandem mass spectrometry, J. Chromatogr. A. 1216 (23) (2009) 4693–4702.

Prieto, A., Basauri, O., Rodil, R., Usobiaga, A., Fernández, L. A., Etxebarria, N., Zuloaga, O. Stir-bar sorptive extraction: a view on method optimisation, novel applications, limitations and potential solutions, J. Chromatogr. A. 1217 (16) (2010) 2642-2666.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2018 Eclética Química Journal

Metrics

PDF views
464
Oct 10 '18Oct 13 '18Oct 16 '18Oct 19 '18Oct 22 '18Oct 25 '18Oct 28 '18Oct 31 '18Nov 01 '18Nov 04 '18Nov 07 '183.0
| |
Other format views
11
Jan 2019Jul 2019Jan 2020Jul 2020Jan 2021Jul 2021Jan 2022Jul 2022Jan 2023Jul 2023Jan 2024Jul 2024Jan 2025Jul 2025Jan 20262.0
|